It’s Round 2 of the 2024/25 EPCR Challenge Cup is here and some teams are already playing for their lives judging by their form and injury curses. It gets harder than ever to predict how the results will play out across the fields of Europe and South Africa, though we can safely say that the South African teams’ missions only get harder this weekend. Check out our predictions and tips before you make your SuperBru picks and bets.

Edinburgh vs Bayonne, Friday, 22:00:
Score: Edinburgh 27-18 Bayonne; SuperBru: Edinburgh by 9 points; Over/Under: -50 points; Handicap:
Montpellier vs Ospreys, Saturday, 15:00:
Score: Montpellier 29-19 Edinburgh; SuperBru: Montpellier by 10 points; Over/Under: -50 points; Handicap:
Zebre vs Lyon, Saturday, 15:00:
Score: Zebre 21-26 Lyon; SuperBru: Lyon by 5 point;s Over/Under: -50 points; Handicap:

Emirates Lions vs Pau, Saturday, 17:15:
Score: Lions 32-18 Pau; SuperBru: Lions by 14 points; Over/Under: +50 points; Handicap:
Vannes vs Gloucester, Saturday, 19:30:
Score: Vannes 23-20 Gloucester; SuperBru: Vannes by 3 points; Over/Under: -50 points; Handicap:
Cardiff Rugby vs Toyota Cheetahs, Saturday, 22:00:
Score: Cardiff 25-24 Cheetahs; SuperBru: Cardiff by 1 point; Over/Under: -50 points; Handicap:

Scarlets vs Black Lion, Sunday, 15:00:
Score: Scarlets 32-17 Black Lion; SuperBru: Scarlets by 15 points; Over/Under: -50 points; Handicap:
Perpignan vs Connacht, Sunday, 15:00:
Score: Perpignan 26-22 Connacht; SuperBru: Perpignan by 4 points; Over/Under: -50 points; Handicap:
Newcastle vs Dragons, Sunday, 17:15:
Score: Newcastle 27-22 Dragons; SuperBru: Newcastle by 5 points; Over/Under: -50 points; Handicap:
